![Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS](https://www.pnas.org/cms/10.1073/pnas.94.7.3004/asset/c7bd61f3-4554-4182-9a49-18c470ea228b/assets/graphic/pq0770168002.jpeg)
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS
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MKK4 plays a central role in SAPK/JNK and p38 signaling. The SAPK/JNK... | Download Scientific Diagram
A Protoberberine Derivative HWY336 Selectively Inhibits MKK4 and MKK7 in Mammalian Cells: The Importance of Activation Loop on Selectivity | PLOS ONE
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MicroRNA-148b regulates tumor growth of non-small cell lung cancer through targeting MAPK/JNK pathway | BMC Cancer | Full Text
A Protoberberine Derivative HWY336 Selectively Inhibits MKK4 and MKK7 in Mammalian Cells: The Importance of Activation Loop on Selectivity | PLOS ONE
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A Vaccinia Virus-Driven Interplay between the MKK4/7-JNK1/2 Pathway and Cytoskeleton Reorganization | Journal of Virology
A Non-Redundant Role for Drosophila Mkk4 and Hemipterous/Mkk7 in TAK1-Mediated Activation of JNK | PLOS ONE
![Arabidopsis E3 ligase KEG associates with and ubiquitinates MKK4 and MKK5 to regulate plant immunity - Gao - 2021 - Journal of Integrative Plant Biology - Wiley Online Library Arabidopsis E3 ligase KEG associates with and ubiquitinates MKK4 and MKK5 to regulate plant immunity - Gao - 2021 - Journal of Integrative Plant Biology - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/3698ac28-ac8b-41de-ab48-61cc1d6af0ba/jipb13007-gra-0001-m.jpg?trick=1671555310719)
Arabidopsis E3 ligase KEG associates with and ubiquitinates MKK4 and MKK5 to regulate plant immunity - Gao - 2021 - Journal of Integrative Plant Biology - Wiley Online Library
![MKK4 and MKK7 have different functions in the developing brain. MKK4... | Download Scientific Diagram MKK4 and MKK7 have different functions in the developing brain. MKK4... | Download Scientific Diagram](https://www.researchgate.net/publication/223993755/figure/fig2/AS:202536079368192@1425299772017/MKK4-and-MKK7-have-different-functions-in-the-developing-brain-MKK4-and-MKK7-both.png)
MKK4 and MKK7 have different functions in the developing brain. MKK4... | Download Scientific Diagram
![Stress-activated JNK pathway. The central MAPKKK (MLK), MAPKK (MKK4/7),... | Download Scientific Diagram Stress-activated JNK pathway. The central MAPKKK (MLK), MAPKK (MKK4/7),... | Download Scientific Diagram](https://www.researchgate.net/publication/47934224/figure/fig8/AS:668270239707145@1536339449766/Stress-activated-JNK-pathway-The-central-MAPKKK-MLK-MAPKK-MKK4-7-MAPK-JNK.png)